THE frq LOCUS IN NEUROSPORA CRASSA: A KEY ELEMENT IN CIRCADIAN CLOCK ORGANIZATION
نویسندگان
چکیده
منابع مشابه
The frq locus in Neurospora crassa: a key element in circadian clock organization.
Four new circadian clock mutants of Neurospora crassa have been isolated that alter the period length of the circadian conidiation rhythm. Three of these are at the frq locus on linkage group VIIR, where four other clock mutants are located. In contrast to wild type, which has a period length of 21.6 hr, frq-6 has a period length of 19 hr, while frq-7 and frq-8 have period lengths of 29 hr and ...
متن کاملCircadian rhythms in Neurospora crassa: clock mutant effects in the absence of a frq-based oscillator.
In Neurospora, the circadian rhythm is expressed as rhythmic conidiation driven by a feedback loop involving the protein products of frq (frequency), wc-1 (white collar-1), and wc-2, known as the frq/wc (FWC) oscillator. Although strains carrying null mutations such as frq(10) or wc-2Delta lack a functional FWC oscillator and do not show a rhythm under most conditions, a rhythm can be observed ...
متن کاملQuantitative trait loci for the circadian clock in Neurospora crassa.
Neurospora crassa has been a model organism for the study of circadian clocks for the past four decades. Among natural accessions of Neurospora crassa, there is significant variation in clock phenotypes. In an attempt to investigate natural allelic variants contributing to quantitative variation, we used a quantitative trait loci mapping approach to analyze three independent mapping populations...
متن کاملA New Mutation Affecting FRQ-Less Rhythms in the Circadian System of Neurospora crassa
We are using the fungus Neurospora crassa as a model organism to study the circadian system of eukaryotes. Although the FRQ/WCC feedback loop is said to be central to the circadian system in Neurospora, rhythms can still be seen under many conditions in FRQ-less (frq knockout) strains. To try to identify components of the FRQ-less oscillator (FLO), we carried out a mutagenesis screen in a FRQ-l...
متن کاملCircadian rhythms in Neurospora crassa: interactions between clock mutations.
Mutations at four loci in Neurospora crassa that alter the period of the circadian rhythm have been used to construct a series of double mutant strains in order to detect interactions between these mutations. Strains carrying mutations at three of these loci have altered periods on minimal media: prd-1, several alleles at the olir (oligomycin resistance) locus and four alleles at the frq locus....
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ژورنال
عنوان ژورنال: Genetics
سال: 1980
ISSN: 1943-2631
DOI: 10.1093/genetics/96.4.877